Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 1.356


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NCOR1chr17_-_16097882-0.801.6e-06Click!
SMARCA5chr4_+_144434555-0.793.1e-06Click!
SMARCC2chr12_-_56583244-0.769.7e-06Click!
SMARCA1chrX_-_128657381-0.701.1e-04Click!
DMAP1chr1_+_44679111-0.096.6e-01Click!
NCOR2chr12_-_125052009-0.048.5e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_101185195 14.529 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr1_-_150738232 7.468 CTSS
cathepsin S
chr15_+_89182038 7.381 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_+_6659356 6.554 XAF1
XIAP associated factor 1
chr1_-_150738255 6.325 CTSS
cathepsin S
chr1_-_150738292 6.168 NM_001199739
NM_004079
CTSS

cathepsin S

chr17_+_6659155 5.608 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr7_-_115670774 5.435 TFEC
transcription factor EC
chr7_-_92777657 5.195 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr10_+_91092238 5.191 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_+_91152321 5.150 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr17_-_34207308 5.046 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr17_-_40264687 4.744 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr8_+_17396285 4.559 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr7_-_115670828 4.511 NM_001018058
NM_012252
TFEC

transcription factor EC

chr9_+_74920329 4.006


chr3_+_122283139 3.905 NM_138287
DTX3L
deltex 3-like (Drosophila)
chr4_-_169239816 3.744 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr6_+_29691116 3.472 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr11_-_104905849 3.466 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr1_+_159175048 3.445 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr11_+_71710662 3.426 NM_001145057
IL18BP
interleukin 18 binding protein
chr6_-_32806545 3.408 NM_000544
NM_018833
TAP2

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

chr4_-_122085475 3.325 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr1_-_12677347 3.170 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr12_+_78225068 3.165 NM_014903
NAV3
neuron navigator 3
chr11_+_71710971 3.118 NM_001145055
IL18BP
interleukin 18 binding protein
chr11_-_104972147 3.011 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr2_+_152214105 2.988 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr7_+_28452143 2.931 NM_182898
CREB5
cAMP responsive element binding protein 5
chr20_+_44746889 2.929 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr11_-_128392061 2.928 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr2_-_37899227 2.917 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr10_-_14372807 2.909 NM_018027
FRMD4A
FERM domain containing 4A
chr21_-_37852387 2.830 NM_001146079
NM_144492
CLDN14

claudin 14

chr5_-_35938736 2.797 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr11_-_8892909 2.756 ST5
suppression of tumorigenicity 5
chr2_+_103035148 2.755 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr1_+_79115476 2.734 NM_006417
IFI44
interferon-induced protein 44
chr7_-_77045706 2.690 NM_017439
PION
pigeon homolog (Drosophila)
chr6_+_26365397 2.586 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr6_-_32806452 2.558 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr12_+_113376001 2.511 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_-_50432672 2.447 IL4I1
interleukin 4 induced 1
chr3_-_122283423 2.399 NM_001146103
NM_031458
PARP9

poly (ADP-ribose) polymerase family, member 9

chr9_+_100174369 2.385 TDRD7
tudor domain containing 7
chr6_+_26402464 2.306 NM_001145008
NM_001145009
NM_007048
NM_194441
BTN3A1



butyrophilin, subfamily 3, member A1



chr19_-_50413063 2.296 NUP62
nucleoporin 62kDa
chr21_+_43919741 2.294 NM_018964
SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr6_-_134498973 2.257 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr14_+_94577078 2.252 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr1_+_948846 2.201 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr6_+_26440699 2.177 NM_001242803
NM_006994
NM_197974
BTN3A3


butyrophilin, subfamily 3, member A3


chr1_+_165796652 2.124 NM_012474
UCK2
uridine-cytidine kinase 2
chr3_-_122283077 2.114 NM_001146102
NM_001146105
NM_001146104
NM_001146106
PARP9



poly (ADP-ribose) polymerase family, member 9



chr7_+_100728719 2.102 NM_030961
TRIM56
tripartite motif containing 56
chr19_+_10197023 2.089 C19orf66
chromosome 19 open reading frame 66
chr19_+_10196972 2.074 C19orf66
chromosome 19 open reading frame 66
chr2_+_143886969 2.058 ARHGAP15
Rho GTPase activating protein 15
chr12_+_11802905 2.037 ETV6
ets variant 6
chr1_+_165797060 2.030 UCK2
uridine-cytidine kinase 2
chr14_+_37126772 1.931 NM_006194
PAX9
paired box 9
chr3_-_157221362 1.912 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr19_-_50432647 1.876 IL4I1
interleukin 4 induced 1
chr9_-_32526164 1.853 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_+_143886898 1.846 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr15_+_97326629 1.808 NM_173499
SPATA8
spermatogenesis associated 8
chr3_+_187086167 1.807 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr11_+_69455938 1.800 CCND1
cyclin D1
chr4_+_89300110 1.771 HERC6
hect domain and RLD 6
chr20_+_44746948 1.768 CD40
CD40 molecule, TNF receptor superfamily member 5
chr11_+_5710926 1.758 TRIM22
tripartite motif containing 22
chr19_-_18508407 1.715 NM_145256
LRRC25
leucine rich repeat containing 25
chr3_-_45267068 1.691 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr12_+_101188373 1.649 NM_178826
ANO4
anoctamin 4
chr1_-_209825797 1.623 NM_000228
LAMB3
laminin, beta 3
chr21_+_42792441 1.569 NM_001144925
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr17_-_39165343 1.557 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr1_+_113217039 1.515 NM_001130079
NM_020963
MOV10

Mov10, Moloney leukemia virus 10, homolog (mouse)

chr1_+_113236679 1.514 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr9_+_96846710 1.494 NM_001253829
NM_152422
PTPDC1

protein tyrosine phosphatase domain containing 1

chr2_-_161130151 1.481 RBMS1
RNA binding motif, single stranded interacting protein 1
chr15_+_67418053 1.480 NM_001145102
SMAD3
SMAD family member 3
chr12_-_16757944 1.468 LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_+_71709951 1.438 NM_001039659
NM_001039660
NM_173044
NM_005699
NM_173042
IL18BP




interleukin 18 binding protein




chr19_-_50432679 1.424 NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr8_-_90996785 1.417 NBN
nibrin
chr19_+_10196757 1.412 NM_018381
C19orf66
chromosome 19 open reading frame 66
chr3_+_31574119 1.406 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr8_-_23540401 1.403 NM_006167
NKX3-1
NK3 homeobox 1
chr3_-_9291251 1.403 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr6_-_143266283 1.392 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr13_-_47470967 1.376 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr20_-_47894591 1.353 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr5_-_27038650 1.343 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr6_+_138188352 1.329 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr17_+_42925278 1.316 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr11_-_64764388 1.289 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr15_-_50411405 1.286 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr16_-_67970651 1.285 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_-_183622447 1.285 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr4_-_169401603 1.283 NM_001012967
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr10_+_114154522 1.268 ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_+_55095433 1.267 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr11_-_84634219 1.247 DLG2
discs, large homolog 2 (Drosophila)
chr19_-_50432678 1.247 NUP62
nucleoporin 62kDa
chr10_+_91061705 1.244 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr5_+_125758818 1.239 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr2_-_100758970 1.237 NM_002285
AFF3
AF4/FMR2 family, member 3
chr11_+_5710816 1.232 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr3_-_27498244 1.231 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr3_+_29322802 1.228 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr5_+_118691692 1.214 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr16_+_50308020 1.183 ADCY7
adenylate cyclase 7
chr1_+_87012758 1.179 NM_012128
CLCA4
chloride channel accessory 4
chr1_-_220101514 1.179 SLC30A10
solute carrier family 30, member 10
chr3_-_71179715 1.177 FOXP1
forkhead box P1
chr16_-_67970734 1.175 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr11_-_8954534 1.175 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr20_-_47894570 1.174 ZNFX1
zinc finger, NFX1-type containing 1
chr2_+_102953716 1.165 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr9_+_100174179 1.150 NM_014290
TDRD7
tudor domain containing 7
chr4_+_55095263 1.144 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr11_-_128391888 1.131 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr12_-_121476770 1.128 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr2_+_228336809 1.124 AGFG1
ArfGAP with FG repeats 1
chr2_-_231989755 1.123 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr4_+_77953942 1.112 SEPT11
septin 11
chr1_+_167298280 1.108 NM_001198783
POU2F1
POU class 2 homeobox 1
chr12_+_11802642 1.107 ETV6
ets variant 6
chr12_-_16758312 1.107 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_+_60869929 1.101 NM_014207
CD5
CD5 molecule
chr6_+_158733691 1.100 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr1_-_209825673 1.080 NM_001127641
LAMB3
laminin, beta 3
chr5_+_131409484 1.068 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr10_+_5772610 1.063 FAM208B
family with sequence similarity 208, member B
chr5_+_113698015 1.060 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr2_+_239756672 1.058 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr2_-_163174816 1.053 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr16_+_57220238 1.036 NM_133368
RSPRY1
ring finger and SPRY domain containing 1
chr10_-_101380086 1.028 SLC25A28
solute carrier family 25, member 28
chr10_-_69455926 1.026 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr1_+_167298382 1.023 POU2F1
POU class 2 homeobox 1
chr11_-_59383179 1.005 OSBP
oxysterol binding protein
chr1_+_15736387 0.997 NM_024329
EFHD2
EF-hand domain family, member D2
chr1_-_200377262 0.991 ZNF281
zinc finger protein 281
chr7_-_92463211 0.985 NM_001259
CDK6
cyclin-dependent kinase 6
chr3_-_50374875 0.978 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr11_+_131240370 0.977 NM_001048209
NTM
neurotrimin
chr16_-_4838316 0.977 NM_001154458
NM_144605
SEPT12

septin 12

chr1_+_15736422 0.967 EFHD2
EF-hand domain family, member D2
chr16_+_30773619 0.962 RNF40
ring finger protein 40
chr2_-_214015053 0.956 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_+_26348488 0.954 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr15_-_89764809 0.943 NM_000326
RLBP1
retinaldehyde binding protein 1
chr1_+_113217466 0.931 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr19_+_15783827 0.922 NM_023944
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr16_-_69385656 0.921 NM_144676
TMED6
transmembrane emp24 protein transport domain containing 6
chr5_-_169724782 0.920 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169724614 0.917 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_84634437 0.917 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr6_+_31913708 0.912 NM_001710
CFB
complement factor B
chr19_+_49497122 0.904 NM_006666
RUVBL2
RuvB-like 2 (E. coli)
chr1_+_32666201 0.902 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr6_+_31913763 0.896 CFB
complement factor B
chr4_+_88896801 0.891 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr20_-_57089845 0.882 NM_153360
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr4_-_48136245 0.874 NM_003328
TXK
TXK tyrosine kinase
chr3_+_119316694 0.874 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr15_-_89878042 0.872 POLG
polymerase (DNA directed), gamma
chr3_-_46718898 0.871 NM_182775
ALS2CL
ALS2 C-terminal like
chr2_+_166428845 0.870 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr4_-_74864296 0.870 NM_002994
CXCL5
chemokine (C-X-C motif) ligand 5
chr6_+_31913852 0.868 CFB
complement factor B
chr15_-_58306185 0.866 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr15_-_101835404 0.866 NM_003090
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr12_+_102271349 0.865 DRAM1
DNA-damage regulated autophagy modulator 1
chr9_-_23826062 0.861 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_174828775 0.859 NM_001017371
SP3
Sp3 transcription factor
chr4_+_175839508 0.855 NM_001130703
NM_001130704
NM_001130705
NM_014269
ADAM29



ADAM metallopeptidase domain 29



chr12_+_41831484 0.854 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr17_+_37784750 0.851 NM_001242464
NM_181505
PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B

chr11_+_64051810 0.846 NM_001170726
GPR137
G protein-coupled receptor 137
chr14_+_55034633 0.844 SAMD4A
sterile alpha motif domain containing 4A
chr11_+_109963524 0.843 ZC3H12C
zinc finger CCCH-type containing 12C
chr3_-_71180061 0.836 NM_001244815
FOXP1
forkhead box P1
chr17_+_78237389 0.833


chr1_+_205198058 0.833 NM_001242925
TMCC2
transmembrane and coiled-coil domain family 2
chr2_-_69098502 0.827 NM_014482
BMP10
bone morphogenetic protein 10
chr1_-_200377488 0.819 ZNF281
zinc finger protein 281
chr6_+_31539875 0.808 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr14_+_58711457 0.803 NM_002788
NM_152132
PSMA3

proteasome (prosome, macropain) subunit, alpha type, 3

chr14_+_21525980 0.796 NM_138331
RNASE8
ribonuclease, RNase A family, 8
chr4_-_89205667 0.795 PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr11_-_18258383 0.792 NM_006512
SAA4
serum amyloid A4, constitutive
chr4_+_88896838 0.791 SPP1
secreted phosphoprotein 1
chr8_-_125579395 0.790 MTSS1
metastasis suppressor 1
chr8_-_145060563 0.785 PARP10
poly (ADP-ribose) polymerase family, member 10
chr19_-_17516383 0.784 NM_004335
BST2
bone marrow stromal cell antigen 2
chr14_+_58711555 0.782 PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.11 9.65e-09 GO:0006955 immune response
1.70 7.19e-06 GO:0002376 immune system process
1.20 1.66e-04 GO:0050789 regulation of biological process
1.17 1.29e-03 GO:0065007 biological regulation
1.19 2.61e-03 GO:0050794 regulation of cellular process
2.09 3.22e-03 GO:0045087 innate immune response
3.88 5.19e-03 GO:0034340 response to type I interferon
1.56 8.10e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.36 1.50e-02 GO:0048519 negative regulation of biological process
3.70 2.06e-02 GO:0060337 type I interferon-mediated signaling pathway
3.70 2.06e-02 GO:0071357 cellular response to type I interferon
2.11 2.21e-02 GO:0034097 response to cytokine stimulus
2.41 2.41e-02 GO:0019221 cytokine-mediated signaling pathway
1.67 2.65e-02 GO:2000026 regulation of multicellular organismal development
1.63 2.85e-02 GO:0006952 defense response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 1.62e-04 GO:0005515 protein binding
1.71 3.39e-03 GO:0043565 sequence-specific DNA binding
2.04 7.23e-03 GO:0016563 transcription activator activity